Coment 1). It is currently thought that there are a number of other additional splice variants of the CaM-dependent PDE gene. These have been described in presentations at meetings by Yan et al and by Loughney et al (see program for Third Intl Conf on cyclic nucleotide phosphodiesterases, July 18, 1996, Glasgow Scotland.)

Comment submitted by J. Beavo, 8/4/97